临床研究:进行4项前瞻性和多个回顾性临床研究,包括反复着床失败和复发性流产人群中免疫检查和代谢因素与IVF结局相关性分析;阿司匹林应用研究;流产先兆特别是宫腔积血对妊娠健康的影响;AMH在不孕不育人群中影响探讨。
基础研究:长期致力于围着床期生殖免疫及母胎界面免疫的机制研究,包括:T细胞、肥大细胞与巨噬细胞在子宫内膜免疫微环境中免疫平衡重建中的机制探讨;阿司匹林对子宫内膜的机制研究;和生殖内分泌紊乱导致子宫内膜容受性下降的病理机制
曾3次获省市科技进步奖(分别为二等奖与三等奖)
中国免疫学会生殖分会常务委员、中国康复医学会产后康复专业委员会常务委员、中国女医师协会母胎医学专业委员会委员;
1. 张珺,黄烁,石婧,刘琼,韩栋林、余晓君、赵捷。尿酸对女性生育力及辅助生殖助孕结局的影响。中华生殖与避孕杂志;2025,45(3):305-309
2.Qiong Liu , Kai-Lun Hu, Jing Shi, Shulin Yang, Yifan Chu, Honghong Wang, Yiwen Zhang, Jing Yue, Guimin Hao, Xueqing Wu, Jie Zhao#, Rong Li#. Association between anti-Müllerian hormone levels during pregnancy and pregnancy outcomes in infertile patients undergoing in vitro fertilisation/ intracytoplasmic sperm injection: protocol for a multicentre prospective cohort study. BMI open. 2025;15:e093543.
3. Yimeng Ge, Shaoyang Lai, Jing Shi, Xin li, Xiaoxue Li, Hongling Chu, Kailun Hu, Rong Li#, Jie Zhao#. Pregnancy outcomes of fetal reduction in patients with intrauterine hematoma following double embryo transfer. Reprod Biomed Online. 2024 Mar; 48(3): 103644.
4. Kai-Lun Hu#, Jie Zhao#, Mingmei Lin, Xiaoye Wang , Linjing Qi , Huan Liu , Dan Mo , Zhonghong Zeng , Ben W Mol , Rong Li .Addition of operative hysteroscopy to vacuum aspiration for the management of early pregnancy loss after in vitro fertilization. Fertil Steril. 2024 Jul 25:S0015-0282(24)00623-X
5. Jing Shi, Kai-Lun Hu, Xiao-Xue Li, Yi-Meng Ge, Xiao-Jun Yu, Jie Zhao.Bisphenol a downregulates GLUT4 expression by activating aryl hydrocarbon receptor to exacerbate polycystic ovary syndrome. Cell Communication and Signaling. 2024 Jan 10;22(1):28.
6. hydrocarbon receptors in nutrient metabolism and immune regulation at the maternal–fetal interface. Placenta. 2024 May 23:154:9-17
7.Ge Y, Lai S, Li X, Shi J, Ma C, Zhao J. Vanishing twin syndrome is associated with first-trimester intrauterine hematoma in twin pregnancies after in vitro fertilization. Front Endocrinol (Lausanne). 2023 Jan 13; 13: 1062303.
8. Shao-Yang Lai, Kai-Lun Hu, Xuan Zhou, Xiao-Xue Li, Xiao-Jun Yu, Jing Shi*, Jie Zhao*. Mechanism of trophoblast cell-derived microparticles mediated immunocontraceptive response. Am J Reprod Immunol. 2023 Jul;90(1):e13712.
9. Han M, Lai S, Ge Y, Zhou X, Zhao J#. Changes of Lipoxin A4 and the Anti‑inflammatory Role During Parturition.Reprod Sci. 2022,29(4):1332-1342.
10. 赵捷*,李小雪,葛逸盟,马彩虹,李蓉。反复着床失败患者预防性免疫治疗后妊娠结局评估,中国免疫学杂志,2021,11月23:83—89
11. Zhou Xuan, Li Xiao Xue, Ge Yi Meng,Lai Shao Yang, Zou Luo Qi, Feng Ling, Zhao Jie#. Effects of vaginal microbiota and cervical cerclage on obstetric outcomes of twin pregnancies with cervical incompetence: a retrospective study. Archives of Gynecology and Obstetrics, 2021, 2021(8): 1-10.
12.赖少阳,周罗绮,周璇,葛逸盟,赵捷#。首次输卵管妊娠对后续宫腔内妊娠结局的影响。华中科技大学学报(医学版),2021,50(1):72—76
13.韩梅,周旋,周罗绮,赖少阳,葛逸盟,赵捷#。环形电刀切除术后宫颈环扎对妊娠结局与阴道微生态的影响。中国微创外科杂志,2021,21(3):243-247
14. Jie Zhao*#, Yuan Yao, Shaoyang Lai, Xuan Zhou. Clinical immunity and medical cost of COVID-19 patients under grey relational mathematical model. Results in Physics. 2021, 22(1):103829