工作经历:2023年6月获北京大学力学(生物力学与医学工程)专业博士学位,2025年4月于北京大学未来技术学院生物医学工程系完成博士后研究。2025年5月入职北京大学第三医工作至今。现任副研究员,负责医工交叉平台的科研工作。
科研工作:围绕“颅颌面组织再生和疾病治疗”开展基于生物医用微球材料的医工交叉研究。主持北京市自然基金2项,博士后面上基金1项,参与国自然面上基金2项。以第一或通讯作者发表论文20篇,被引用超过1700次,H指数22。
学术兼职:受邀为Chem. Eng. J;Mater. Today Bio;Int. J. Biol. Macromol等国际期刊审稿。
代表性论文:
1.Gao, Y.#; Yuan, X.#; Gu, R.#; Wang, N.; Ren, H.; Song, R.; Wan, Z.; Huang, J. *; Yi, K.; Xiong, C.; Yuan, Z.*; Zhao, Y.* The affinity modifications of porous micro-scaffolds impact bone regeneration by modulating the delivery kinetics of small extracellular vesicles. ACS Nano 2025, 19(18), 17813-17823.
2.Feng, Y.; Xie, W.; Wan, Z.; Jiang, Y.; Xu, H.; Qu, J.; Tian, Z.; Liu, Y.; Liu, X.; Yuan, Z.*; Qin, S.; Xiong, C.*; Huang, J. *. Harnessing RGDS peptides to regulate bacterial-host interfaces for targeted antimicrobial therapy. Journal of Controlled Release 2025, 384, 113922.
3.Yuan, X.#; Wang, S.#; Yuan, Z.*; Wan, Z.; Zhang, L.; Song, R.; Ge, L. *; Zhao, Y. * Boosting the angiogenesis potential of self-assembled mesenchymal stem cell spheroids by size mediated physiological hypoxia for vascularized pulp regeneration. Acta Biomaterialia 2025, 198, 102-114.
4.Wang, X.#; Wan, Z.#; Yang, S.; Ma, L.; Zhan, Q.; Jin, J.*; Yuan, Z.* Natural β-carotene based nanodrug: a promising phosphatidylinositol 3-kinase targeting strategy to treat oral carcinogenesis. Chemical Engineering Journal, 2024, 497, 154600.
5.Yuan, Z.#; Duan, X.#; Su, X.; Tian, Z.; Jiang, A.; Wan, Z. Wang, H.; Wei, P.; Zhao, B.; Liu, X.; Huang, J.* Catch bond-inspired hydrogels with repeatable and loading rate-sensitive specific adhesion. Bioactive Materials 2023, 21, 566-575.
6.Yuan, Z.; Wan, Z.; Gao, C.; Wang, Y.; Huang, J.*; Cai, Q.*, Controlled magnesium ion delivery system for in situ bone tissue engineering. Journal of Controlled Release 2022, 350, 360-376.
7.Wan, Z.#; Yuan, Z.#; Li, Y.; Zhang, Y.; Wang, Y.; Yu, Y.*; Mao, J.; Cai, Q.*; Yang, X. Hierarchical therapeutic ion-based microspheres with precise ratio-controlled delivery as microscaffolds for in situ vascularized bone regeneration. Advanced Functional Materials 2022, 32, 2113280.
8.Yuan, Z.#; Wan, Z.#; Tian, Z.; Han, Y.; Huang, X.; Feng, Y.; Xie, W.; Duan, X.; Huang, S.; Liu, X.; Huang, J.* In situ fused granular hydrogels with ultrastretchability, strong adhesion, and mutli-bioactivities for efficient chronic wound care. Chemical Engineering Journal 2022, 450, 138076.
9.Wang, X.#; Yuan, Z.#; Tao, A.#; Wang, P.; Xie, W.; Yang, S.; Huang, J.*; Wen, N.* Hydrogel-based patient-friendly photodynamic therapy of oral potentially malignant disorders. Biomaterials 2022, 281, 121377.
10.Yuan, Z.#; Yuan, X.#; Zhao, Y.*; Cai, Q.; Wang, Y.; Luo, R.; Yu, S.; Wang, Y.; Han, J.; Ge, L.*; Huang, J.; Xiong, C.* Injectable GelMA cryogel microspheres for modularized cell delivery and potential vascularized bone regeneration. Small 2021, 17, e2006596
专利项目:
1. 发明专利:王兴;袁作楹;黄建永;陶安琪;刘宏伟;韩莹;一种用于口腔癌前病变光动力治疗的干式凝胶贴片及其制备方法,ZL202110618873.9
2. 发明专利:蔡晴;袁作楹;魏鹏飞;杨小平;万卓;具有可控镁离子释放行为的可注射骨修复材料及其制备方法,ZL201810093484.7
3. 发明专利:黄建永;袁作楹;苏醒;多功能特异性生物粘合水凝胶、制备方法及其应用,ZL202010252636.
4. 发明专利:蔡晴;魏鹏飞;袁作楹;杨小平;黄丹妮;一种具有抑菌-促成骨双功能的多孔微球细胞支架及其制备方法,ZL201810112158.
5.发明专利:黄建永;解文月;田卓灵;袁作楹;万卓;替代可吸收缝合线的脂肪组织粘合剂、制备方法及其应用,ZL202211178309.0
著作或译著:
参编《Bioactive Materials for Soft Tissue Regeneration》